Efg1 Involved in Drug Resistance by Regulating the Expression of ERG3 in Candida albicans
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چکیده
منابع مشابه
Efg1 involved in drug resistance by regulating the expression of ERG3 in Candida albicans.
The ERG3 gene in Candida albicans was identified as a gene whose mRNA level was higher in the cph1/cph1 efg1/efg1 double mutant than in the wild-type cells. Further study showed that Efg1, but not Cph1, negatively regulated ERG3. Mutations in EFG1 consistently increased the susceptibility of the cells to antifungal agents.
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2005
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.49.3.1213-1215.2005